abstract：:The duration of diabetes before puberty is not considered relevant to the future development of complications. To evaluate the effects of diabetes on the neural retina, we analysed macular function by steady-state focal electroretinography in 20 prepubescent diabetic children without vascular retinopathy and in 39 sex...

journal_title：Acta diabetologica

authors： Greco AV,Di Leo MA,Caputo S,Falsini B,Porciatti V,Marietti G,Ghirlanda G

更新日期：1994-06-01 00:00:00

abstract：:The aim of this study was to assess the effectiveness and safety of intracavernous injections of a four-drug vasoactive mixture in diabetic patients with organic impotence. A group of 60 diabetic patients with either pure neurogenic, pure vasculogenic or mixed neurovasculogenic impotence were treated with intracaverno...

journal_title：Acta diabetologica

authors： Montorsi F,Guazzoni G,Bergamaschi F,Zucconi M,Rigatti P,Pizzini G,Miani A,Pozza G

更新日期：1994-04-01 00:00:00

abstract：:Hypertriglyceridaemia is associated with insulin resistance of both lipid and glucose metabolism. It is not known whether the insulin resistance affects both glucose oxidation and glycogen formation. To study the oxidative and non-oxidative pathways of non-esterified fatty acids (NEFA) and glucose metabolism, eight ma...

journal_title：Acta diabetologica

authors： Saloranta C,Groop L,Ekstrand A,Franssila-Kallunki A,Taskinen MR

更新日期：1994-04-01 00:00:00

abstract：:The effect of a phenacyl imidazolium compound (LY177507 or Proglycosyn, Eli Lilly) on the direct (glucose-->glucose-6-phosphate-->glycogen) and indirect (three-carbon compounds-->glucose-6-phosphate-->glycogen) pathways of liver glycogen synthesis was studied in conscious rats. [1-13C]Glucose (99% enriched) was infuse...

journal_title：Acta diabetologica

authors： Cline GW,Greenawalt K,Shulman GI

更新日期：1993-01-01 00:00:00

abstract：:Insulin secretion is stimulated better by oral than by intravenous glucose (incretin effect). The contribution of the autonomic nervous system to the incretin effect after oral glucose in humans is unclear. We therefore examined nine type 1 diabetic (insulin-dependent) patients with end-stage nephropathy, studied afte...

journal_title：Acta diabetologica

authors： Nauck MA,Büsing M,Orskov C,Siegel EG,Talartschik J,Baartz A,Baartz T,Hopt UT,Becker HD,Creutzfeldt W

更新日期：1993-01-01 00:00:00

abstract：:The original report on the microencapsulation of islets of Langerhans used sodium alginate and poly-L-lysine (PLL) to form the capsules. Although several alternative materials have subsequently been used with vary-mg degrees of success, it is those studies using islets encapsulated in alginate-PLL-alginate which are r...

journal_title：Acta diabetologica

authors： Clayton HA,James RF,London NJ

更新日期：1993-01-01 00:00:00

abstract：:Selective loss of capillary pericytes occurs early and specifically in diabetic retinopathy. We have investigated whether blood derivatives from patients with long-term type 1 (insulin-dependent) diabetes and no retinopathy differ from those with retinopathy and/or non-diabetic controls in their ability to stimulate D...

journal_title：Acta diabetologica

authors： Williams FM,Dosso AA,Kohner EM,Porta M

更新日期：1993-01-01 00:00:00

abstract：:The purification of large numbers of human pancreatic islets remains one of the limiting factors in islet transplantation. This paper describes and validates a method for accurately and reproducibly determining the density of islets and exocrine tissue in pancreatic digest on the basis of their isopycnic distribution ...

journal_title：Acta diabetologica

authors： Robertson GS,Chadwick DR,Contractor H,James RF,Bell PR,London NJ

更新日期：1993-01-01 00:00:00

abstract：:Postreceptor insulin resistance was studied in liver, muscle and adipose tissue from NMRI mice of both sexes made diabetic by long-term fat-feeding. Intravenous glucose tolerance tests showed a combination of impaired glucose tolerance and increased plasma insulin concentrations consistent with insulin resistance and ...

journal_title：Acta diabetologica

authors： Hedeskov CJ,Capito K,Islin H,Hansen SE,Thams P

更新日期：1992-01-01 00:00:00

abstract：:HLA-A, B, C, DR and DQ typing was performed in 381 Italian insulin-dependent diabetic patients and in 905 normal Italian subjects. The diabetic patients had significantly higher frequencies of HLA-Cw7, B8, B18, DR3, DR4, DQw2 and DQw3 and significantly lower frequencies of HLA-B17, Bw51, DR2, DR7 and DRw11. The freque...

journal_title：Acta diabetologica

authors： Bognetti E,Meschi F,Malavasi C,Pastore MR,Sergi A,Illeni MT,Maffeis C,Pinelli L,Chiumello G

更新日期：1992-01-01 00:00:00

abstract：:Type 2, non-insulin-dependent diabetes mellitus accounts for 60% of the end-stage renal disease attributed to diabetes in the United States, yet little is known about glomerular function or the development of renal disease in this type of diabetes. The Diabetic Renal Disease Study (DRDS) is a longitudinal study design...

journal_title：Acta diabetologica

authors： Nelson RG

更新日期：1991-01-01 00:00:00